Substance Use & Addictions

Substance-Related and Addictive Disorders (DSM-5-TR)

Compulsive use despite consequences, tolerance, withdrawal, and functional impairment. Includes alcohol, opioids, stimulants, cannabis, and behavioral addictions. Psychosocial recommendations vary by substance, treatment goal, and stage of recovery.

Prevalence: ~17% of Americans aged 12 and older met criteria for a substance use disorder in the past year (16.8%, or 48.4 million people, NSDUH 2024)

Clinical Picture

Substance use disorders sit at the intersection of neurobiology, psychology, social context, and meaning. The field has moved substantially from the moral model ('addiction as character flaw') and even from the pure disease model toward a more integrated understanding that includes developmental trauma, affect dysregulation, social determinants, and the genuine (if destructive) function that substances serve. Motivational Interviewing's foundational insight, that ambivalence about change is normal, not pathological, has transformed how clinicians across all modalities approach substance use.

Treatment Considerations

Two medical facts sit underneath everything else here. Withdrawal from alcohol and from benzodiazepines can kill and needs medical management, unlike opioid withdrawal, which is agonizing but rarely dangerous; students often have this backwards. And tolerance falls during any period of abstinence, which makes the weeks after a treatment episode, a hospitalization, or a jail release the highest-risk window for fatal opioid overdose, so naloxone and medications for opioid use disorder belong in the plan alongside therapy. Beyond that: Motivational Interviewing is the entry point for many clients who are ambivalent about change. CBT-based approaches (including relapse prevention) address the cognitive and behavioral patterns that maintain use. Contingency Management has some of the strongest effect sizes in the addiction literature but remains underused due to implementation challenges. For clients whose substance use is intertwined with trauma history (which is the majority), integrated treatment that addresses both simultaneously outperforms sequential treatment. 12-step facilitation remains widely available and effective for many, though its spiritual framework isn't a fit for everyone.


Approaches and Evidence

Of 29 associated approaches, 3 have completed assessments for this topic, 13 have source checks awaiting assessment, and 13 have neither recorded yet. Each completed assessment states its population and rationale; source checks alone do not establish effectiveness. These categories describe different findings and review stages; they are not a ranking of treatments.

Guideline recommendation (3)

These assessments record a guideline recommendation for the stated population. Read the scope and rationale; a broad topic label does not make a recommendation applicable to everyone.

Integrative

12-Step Facilitation

Nowinski / Baker / Carroll · 1992

Reviewed population: Adults with alcohol use disorder pursuing abstinence, including early recovery or after relapse, when 12-step involvement fits their preferences.

VA/DoD 2021 includes 12-step facilitation among AUD psychosocial options (15, Weak for; low-quality evidence). In early recovery or after relapse, recommendation 28 is Strong for systematic mutual-help engagement, with moderate-quality evidence, and includes 12-step facilitation among three options. Preference and availability matter. TSF is professional facilitation of 12-step participation, not a requirement that everyone attend AA; this abstinence-oriented option is not suited to a controlled-drinking goal.

Reviewed

Guidelines and official sources (3)

3 clinical guideline checks

Read the recommendation and its scope. A source may discuss an approach without recommending it.

  • Clinical Practice Guideline for the Management of Substance Use Disorders

    VA/DoD · August 2021; version 5.0 · Clinical guideline · Recommendations 15, 28–29; pp.30, 32, 72–75

    Recommendation for the stated population

    VA/DoD suggests TSF for alcohol-use-disorder treatment. It also supports systematic mutual-help engagement, including TSF: strongly for alcohol recovery and weakly for drug-use-disorder recovery.

    Scope: Alcohol-use-disorder treatment, and mutual-help engagement during early recovery or after relapse from alcohol or drug-use disorders.

    Source checked

  • Mental Health Gap Action Programme (mhGAP) guideline for mental, neurological and substance use disorders

    World Health Organization · Third edition, 20 November 2023 · Clinical guideline · DRU3 justification, p. 70 (PDF p. 102)

    Discussed in the source

    WHO reports uncertainty about the effects of a 12-step approach compared with no treatment or usual care. DRU3 recommends CBT and contingency management; it does not positively recommend a 12-step protocol here.

    Scope: Adults with cocaine or stimulant dependence.

    Source checked

  • Mental Health Gap Action Programme (mhGAP) guideline for mental, neurological and substance use disorders

    World Health Organization · Third edition, 20 November 2023 · Clinical guideline · ALC2, pp. 13–14 (PDF pp. 45–46)

    Discussed in the source

    12-step facilitation is discussed within the reviewed psychosocial interventions. WHO conditionally recommends structured psychosocial treatment as a group, with low-certainty evidence, while noting uncertainty about individual therapy types versus usual care.

    Scope: Adults with alcohol dependence.

    Source checked

Cognitive-Behavioral

Cognitive Behavioral Therapy

Aaron Beck · 1964

Reviewed population: Adults with harmful drinking or mild alcohol dependence, using CBT focused on alcohol-related problems.

NICE CG115 recommendation 1.3.3.1 offers an alcohol-focused psychological intervention, including cognitive behavioral therapies, for this population; 1.3.3.5 describes delivery. This assessment covers that alcohol-specific application of CBT, not every substance-use diagnosis or the medical management of withdrawal.

Reviewed

Guidelines and official sources (5)

5 clinical guideline checks

Read the recommendation and its scope. A source may discuss an approach without recommending it.

  • Clinical Practice Guideline for the Management of Substance Use Disorders

    VA/DoD · August 2021; version 5.0 · Clinical guideline · Recommendations 15, 23 and 26; pp.30–32, 52, 65, 69

    Recommendation for the stated population

    VA/DoD includes CBT among treatment options: weak recommendations for alcohol and cannabis use disorders, and a strong recommendation for initial cocaine-use-disorder treatment. Preference and availability guide selection.

    Scope: Adults with alcohol-, cannabis-, or cocaine-use disorder.

    Source checked

  • Clinical Practice Guideline for Tobacco Use Treatment

    VA/DoD · January 2026; version 3.0 · Clinical guideline · Recommendations 13 and 15; pp.36, 50–54; Appendix I, p.129

    Insufficient evidence for or against

    VA/DoD strongly supports more intensive counseling and finds insufficient evidence to prefer another counseling approach over standard CBT. That comparative uncertainty is not a recommendation against CBT.

    Scope: Behavioral counseling for adult tobacco cessation.

    Source checked

  • Clinical Practice Guideline for the Treatment of Posttraumatic Stress Disorder in Adults

    American Psychological Association · Approved February 2025; 2025 update · Clinical guideline · PTSD and substance-use disorder, printed p.15 (PDF p.19)

    Recommendation for the stated population

    APA strongly recommends adding trauma-focused treatment in this specific combined-care comparison.

    Scope: Adults with PTSD and co-occurring SUD; trauma-focused CBT plus usual SUD care versus usual SUD care alone.

    Source checked

  • Psychosocial support for psychostimulant use disorders

    World Health Organization · 2023 update; earlier 2012 recommendation · Clinical guideline · DRU3, pp. 69–70 (PDF pp. 101–102); 2023 recommendation block

    Recommendation for the stated population

    WHO strongly recommends CBT, with low-certainty evidence. This finding is specific to cocaine and stimulant dependence, rather than all substance use conditions.

    Scope: Adults with cocaine or stimulant dependence.

    Source checked

  • Mental Health Gap Action Programme (mhGAP) guideline for mental, neurological and substance use disorders

    World Health Organization · Third edition, 20 November 2023 · Clinical guideline · ALC2, pp. 13–14 (PDF pp. 45–46)

    Discussed in the source

    CBT is discussed within the reviewed psychosocial interventions. WHO conditionally recommends structured psychosocial treatment as a group, with low-certainty evidence, while noting uncertainty about individual therapy types versus usual care.

    Scope: Adults with alcohol dependence.

    Source checked

Behavioral

Contingency Management

Higgins / Petry · 1991

Reviewed population: Adults with stimulant use disorder, including cocaine or amphetamine/methamphetamine use disorder, receiving other psychosocial treatment.

ASAM/AAAP recommendation 5 gives a strong recommendation, with high certainty, for contingency management as a primary treatment component alongside other psychosocial interventions. VA/DoD 2021 recommends it with another behavioral intervention for cocaine use disorder (26, Strong for), and suggests that combination for amphetamine/methamphetamine use disorder (27, Weak for). These statements do not establish the same recommendation for alcohol or every substance-use disorder.

Reviewed

Guidelines and official sources (8)

6 clinical guideline checks · 1 research recommendations check · 1 regulatory source check

Read the recommendation and its scope. A source may discuss an approach without recommending it.

  • CG115 recommendations for research

    NICE · 2011; updated 2014 · Research recommendations · Research recommendation 1

    Research recommendation

    NICE identifies an alcohol research question and asks for a trial. This is not a clinical recommendation to offer CM, nor a prohibition on use outside research.

    Scope: Research into contingency management for alcohol-related problems.

    Source checked

  • Drug misuse in over 16s: psychosocial interventions (CG51)

    NICE · 2007; current indexed recommendation page checked 2026-09-06 · Clinical guideline · Recommendations 1.4.1.1–1.4.1.4

    Recommendation for the stated population

    NICE recommends introducing CM programs for these drug-treatment populations. This does not turn the separate alcohol research question into a clinical recommendation.

    Scope: Over 16s receiving methadone maintenance or primarily misusing stimulants.

    Source checked

  • Using SAMHSA Funds to Implement Evidence-Based Contingency Management Services

    SAMHSA · January 2025 · Regulatory source · January 2025 advisory, p.1

    Discussed in the source

    The January 2025 advisory documents funding and implementation conditions. It is a funding policy, not confirmation of the record’s 2023 date or a universal treatment mandate.

    Scope: Authorized SAMHSA grants that include approved contingency-management activities.

    Source checked

  • Clinical Practice Guideline for the Management of Substance Use Disorders

    VA/DoD · August 2021; version 5.0 · Clinical guideline · Recommendations 26–27; pp.32, 69–71

    Recommendation for the stated population

    VA/DoD recommends CM combined with another behavioral intervention for cocaine-use disorder and suggests that combination for amphetamine/methamphetamine-use disorder. The respective strengths are strong and weak.

    Scope: Initial treatment of cocaine- or amphetamine/methamphetamine-use disorder.

    Source checked

  • Clinical Practice Guideline for Tobacco Use Treatment

    VA/DoD · January 2026; version 3.0 · Clinical guideline · Recommendation 31; pp.38, 75–77

    Recommendation for the stated population

    VA/DoD weakly recommends CM or incentives in combination with behavioral counseling and pharmacotherapy. The recommendation is for this combined treatment package.

    Scope: Adult tobacco or nicotine use treatment.

    Source checked

  • Psychosocial support for psychostimulant use disorders

    World Health Organization · 2023 update; earlier 2012 recommendation · Clinical guideline · DRU3, pp. 69–70 (PDF pp. 101–102); 2023 recommendation block

    Recommendation for the stated population

    WHO strongly recommends contingency management, with low-certainty evidence. This finding is specific to cocaine and stimulant dependence, rather than all substance use conditions.

    Scope: Adults with cocaine or stimulant dependence.

    Source checked

  • Mental Health Gap Action Programme (mhGAP) guideline for mental, neurological and substance use disorders

    World Health Organization · Third edition, 20 November 2023 · Clinical guideline · ALC2, pp. 13–14 (PDF pp. 45–46)

    Discussed in the source

    Contingency management is discussed within the reviewed psychosocial interventions. WHO conditionally recommends structured psychosocial treatment as a group, with low-certainty evidence, while noting uncertainty about individual therapy types versus usual care.

    Scope: Adults with alcohol dependence.

    Source checked

  • The ASAM/AAAP Clinical Practice Guideline on the Management of Stimulant Use Disorder

    American Society of Addiction Medicine / American Academy of Addiction Psychiatry · Released November 2023; journal publication 2024 · Clinical guideline · Recommendation 5; printed p.8, PDF p.9

    Recommendation for the stated population

    Strong recommendation with high certainty for contingency management as a primary component of treatment; scope is stimulant use disorder.

    Scope: Stimulant use disorder; contingency management alongside other psychosocial interventions.

    Source checked

Source checks available — assessment pending (13)

Sources have been checked for this topic, but a condition-specific assessment has not been completed. Open the source notes to read each document’s population, recommendation and limitations.

Cognitive-Behavioral

Acceptance and Commitment Therapy

Steven Hayes · 1999

Guidelines and official sources (2)

2 clinical guideline checks

Read the recommendation and its scope. A source may discuss an approach without recommending it.

  • Clinical Practice Guideline for the Management of Substance Use Disorders

    VA/DoD · August 2021; version 5.0 · Clinical guideline · Recommendation 30; pp.33, 75–76

    Insufficient evidence for or against

    The guideline reviews ACT studies and finds insufficient evidence for or against the broader mindfulness-based treatment category. This is a neutral finding for this substance-use scope.

    Scope: ACT within the review of mindfulness-based treatments for substance-use disorders.

    Source checked

  • Clinical Practice Guideline for Tobacco Use Treatment

    VA/DoD · January 2026; version 3.0 · Clinical guideline · Recommendation 15; pp.36, 53–54; Appendix I, p.129

    Insufficient evidence for or against

    The guideline discusses ACT and finds insufficient evidence to recommend a specific behavioral counseling approach over standard CBT. Its description of ACT is not a separate positive recommendation.

    Scope: ACT compared with standard CBT for adult tobacco cessation.

    Source checked

Cognitive-Behavioral

Behavioral Couples Therapy

Neil Jacobson / Gayla Margolin (after Stuart, Weiss) · 1979

Guidelines and official sources (2)

2 clinical guideline checks

Read the recommendation and its scope. A source may discuss an approach without recommending it.

  • Alcohol-use disorders: diagnosis, assessment and management (CG115)

    NICE · 2011 · Clinical guideline · 1.3.3.2 and 1.3.3.8

    Discussed in the source

    NICE recommends alcohol-focused behavioural couples therapy in this specified context, with explicit domestic-abuse exclusions. This alcohol-treatment adaptation is not a separate endorsement of every traditional couples-therapy protocol.

    Scope: Harmful drinking or mild alcohol dependence; willing regular partner; excludes indicators of currently experiencing or perpetrating domestic abuse

    Source checked

  • Clinical Practice Guideline for the Management of Substance Use Disorders

    VA/DoD · August 2021; version 5.0 · Clinical guideline · Recommendation 15; pp.30, 52; Appendix C, pp.115–116

    Discussed in the source

    VA/DoD weakly recommends the alcohol-focused adaptation, which includes sobriety support and relationship work. This source does not separately endorse IBCT or all applications of couples therapy.

    Scope: Behavioral couples therapy adapted for adults with alcohol-use disorder and a participating partner.

    Source checked

Family Systems

Brief Strategic Family Therapy

Jose Szapocznik · 1978

Guidelines and official sources (3)

2 clinical guideline checks · 1 professional reference check

Read the recommendation and its scope. A source may discuss an approach without recommending it.

  • Brief Strategic Family Therapy for Adolescent Drug Abuse

    National Institute on Drug Abuse · 2003; Therapy Manual 5; NIH publication 03-4751 · Professional reference · Chapter 1: overview

    Discussed in the source

    NIDA published a research-based BSFT treatment manual. Publication and dissemination are different from a contemporary graded clinical recommendation.

    Scope: Adolescent drug use with co-occurring behavioral problems.

    Source checked

  • Alcohol-use disorders: diagnosis, assessment and management (CG115)

    NICE · 2011 · Clinical guideline · Recommendations 1.3.7.8 and 1.3.7.11

    Recommendation for the stated population

    NICE names BSFT among multicomponent programmes to offer for this alcohol-use population, and specifies its family-focused delivery.

    Scope: BSFT for ages 10–17 with alcohol misuse and significant comorbidity or limited support.

    Source checked

  • Psychosocial support for psychostimulant use disorders

    World Health Organization · 2023 update; earlier 2012 recommendation · Clinical guideline · 2012 recommendation and 2023 update; DRU3, pp. 69–70 (PDF pp. 101–102)

    Discussed in the source

    The 2012 conditional recommendation included family therapy broadly. The 2023 update recommends CBT and contingency management; family and couples therapy were excluded from that review. Neither passage separately recommends BSFT.

    Scope: Psychosocial treatment for cocaine or stimulant dependence.

    Source checked

Cognitive-Behavioral

Community Reinforcement Approach

George Hunt / Nathan Azrin · 1973

Guidelines and official sources (4)

2 clinical guideline checks · 2 professional reference checks

Read the recommendation and its scope. A source may discuss an approach without recommending it.

  • Principles of Drug Addiction Treatment: A Research-Based Guide, Third Edition

    National Institute on Drug Abuse (NIDA) · Revised January 2018 · Professional reference · Evidence-Based Approaches: CRA Plus Vouchers, PDF p.33

    Discussed in the source

    NIDA describes a combined CRA-plus-vouchers intervention in its research-based guide. This is not a graded recommendation for every CRA use.

    Scope: CRA plus vouchers for substance-use treatment.

    Source checked

  • TIP 34: Brief Interventions and Brief Therapies for Substance Abuse, Chapter 4

    SAMHSA / Center for Substance Abuse Treatment · 1999 · Professional reference · Chapter 4: Community Reinforcement Approach

    Discussed in the source

    SAMHSA discusses CRA in a treatment-improvement protocol. This source does not establish the separately claimed historical registry listing.

    Scope: Behavioral treatment of alcohol and other substance-use problems.

    Source checked

  • Clinical Practice Guideline for the Management of Substance Use Disorders

    VA/DoD · August 2021; version 5.0 · Clinical guideline · Recommendations 15 and 26; pp.30, 32, 69–70; Appendix C, p.116

    Recommendation for the stated population

    VA/DoD suggests CRA for alcohol-use disorder and includes it among strongly recommended recovery-focused options for cocaine-use disorder. The combination requirement in recommendation 26 applies to the separate CM option.

    Scope: Adults with alcohol-use disorder or initial cocaine-use-disorder treatment.

    Source checked

  • Mental Health Gap Action Programme (mhGAP) guideline for mental, neurological and substance use disorders

    World Health Organization · Third edition, 20 November 2023 · Clinical guideline · DRU3 remarks, p. 70 (PDF p. 102)

    Discussed in the source

    The review includes community reinforcement within the cognitive-behavioral approach category. DRU3 recommends CBT and contingency management; it does not separately grade CRA.

    Scope: Adults with cocaine or stimulant dependence.

    Source checked

Family Systems

Functional Family Therapy

Alexander / Parsons · 1973

Guidelines and official sources (3)

1 clinical guideline check · 1 evidence registry check · 1 professional reference check

Read the recommendation and its scope. A source may discuss an approach without recommending it.

  • Functional Family Therapy (FFT): program profile

    Blueprints for Healthy Youth Development, University of Colorado Boulder · Current profile checked 2026-09-06; no revision date shown · Evidence registry · Endorsements; Generalizability

    Discussed in the source

    The current Blueprints profile rates FFT Promising. Older descriptions of Model Plus should not be presented as the current rating. This is a registry, not a clinical guideline.

    Scope: Adolescent behavior, offending and substance-use research.

    Source checked

  • TIP 39: Substance Use Disorder Treatment and Family Therapy, Chapter 3

    SAMHSA · 2020 update · Professional reference · Chapter 3: Functional Family Therapy

    Discussed in the source

    SAMHSA TIP 39 discusses FFT and supporting research. The discussion is separate from a clinical recommendation for all childhood conditions.

    Scope: Family treatment for substance-use problems.

    Source checked

  • Alcohol-use disorders: diagnosis, assessment and management (CG115)

    NICE · 2011 · Clinical guideline · Recommendations 1.3.7.8 and 1.3.7.12

    Recommendation for the stated population

    NICE includes FFT as an example of a multicomponent program to offer in this defined population.

    Scope: Ages 10–17 with alcohol misuse and significant comorbidity and/or limited social support.

    Source checked

Cognitive-Behavioral

Internet-Delivered Cognitive Behavioral Therapy

Various (Andersson / Titov) · 2000

Guidelines and official sources (1)

1 clinical guideline check

Read the recommendation and its scope. A source may discuss an approach without recommending it.

  • Clinical Practice Guideline for the Management of Substance Use Disorders

    VA/DoD · August 2021; version 5.0 · Clinical guideline · Recommendation 35; pp.33, 81–82

    Insufficient evidence for or against

    VA/DoD finds insufficient evidence for or against these treatments. Its review includes CBT4CBT and distinguishes computerized treatment from live therapist telemedicine and text-message support.

    Scope: Computer-delivered CBT and other behavioral treatments for substance-use disorders, alone or alongside usual care.

    Source checked

Contemplative

Mindfulness-Based Relapse Prevention

Sarah Bowen / Neha Chawla / G. Alan Marlatt · 2010

Guidelines and official sources (3)

3 clinical guideline checks

Read the recommendation and its scope. A source may discuss an approach without recommending it.

  • Clinical Practice Guideline for the Management of Substance Use Disorders

    VA/DoD · August 2021; version 5.0 · Clinical guideline · Recommendation 30; pp.33, 75–76

    Insufficient evidence for or against

    VA/DoD finds insufficient evidence for or against mindfulness-based therapies. It discusses MBRP directly, but does not make a positive recommendation for it.

    Scope: Mindfulness-based therapies, including MBRP, for substance-use disorders.

    Source checked

  • Mental Health Gap Action Programme (mhGAP) guideline for mental, neurological and substance use disorders

    World Health Organization · Third edition, 20 November 2023 · Clinical guideline · ALC2, pp. 13–14 (PDF pp. 45–46)

    Discussed in the source

    Mindfulness-based relapse prevention is discussed within the reviewed psychosocial interventions. WHO conditionally recommends structured psychosocial treatment as a group, with low-certainty evidence, while noting uncertainty about individual therapy types versus usual care.

    Scope: Adults with alcohol dependence.

    Source checked

  • Clinical Practice Guideline for Tobacco Use Treatment

    VA/DoD · January 2026; version 3.0 · Clinical guideline · Recommendation 28; Table 4, p.38; discussion pp.70–72

    Discussed in the source

    VA/DoD weakly recommends against standalone mindfulness for this cessation goal. This is category-level guidance; MBRP is not separately graded, and the statement does not address adjunctive use or other conditions.

    Scope: Mindfulness used as a standalone treatment for abstinence from tobacco or nicotine.

    Source checked

Humanistic

Motivational Enhancement Therapy

William Miller (Project MATCH) · 1993

Guidelines and official sources (4)

4 clinical guideline checks

Read the recommendation and its scope. A source may discuss an approach without recommending it.

  • Alcohol-use disorders: diagnosis, assessment and management (CG115)

    NICE · 2011 · Clinical guideline · Recommendation 1.3.1.1

    Discussed in the source

    NICE recommends a motivational intervention containing key elements of motivational interviewing. This passage does not separately recommend the full MET protocol.

    Scope: Initial assessment of people who misuse alcohol.

    Source checked

  • Clinical Practice Guideline for the Management of Substance Use Disorders

    VA/DoD · August 2021; version 5.0 · Clinical guideline · Recommendations 15 and 23; pp.30–31, 52, 65; Appendix C, p.117

    Recommendation for the stated population

    VA/DoD suggests MET among treatment options for both disorders, considering preference and availability. These are weak recommendations for the structured MET intervention, rather than a single brief conversation.

    Scope: Adults with alcohol- or cannabis-use disorder.

    Source checked

  • Clinical Practice Guideline for the Treatment of Posttraumatic Stress Disorder in Adults

    American Psychological Association · Approved February 2025; 2025 update · Clinical guideline · PTSD and substance-use disorder, printed p.15 (PDF p.19)

    Insufficient evidence for or against

    APA finds insufficient evidence to prefer sequential over concurrent delivery, or vice versa. This is not a recommendation about MET alone.

    Scope: Adults with PTSD and co-occurring SUD; MET followed by PE versus MET delivered with PE.

    Source checked

  • Mental Health Gap Action Programme (mhGAP) guideline for mental, neurological and substance use disorders

    World Health Organization · Third edition, 20 November 2023 · Clinical guideline · DRU3 remarks, p. 70 (PDF p. 102)

    Discussed in the source

    Motivational enhancement is included in the reviewed motivational-interviewing category. The positive recommendation names CBT and contingency management, rather than MET.

    Scope: Adults with cocaine or stimulant dependence.

    Source checked

Humanistic

Motivational Interviewing

Miller / Rollnick · 1983

Guidelines and official sources (6)

5 clinical guideline checks · 1 professional reference check

Read the recommendation and its scope. A source may discuss an approach without recommending it.

  • Alcohol-use disorders: diagnosis, assessment and management (CG115)

    NICE · 2011 · Clinical guideline · 1.3.1.1

    Recommendation for the stated population

    NICE recommends an initial motivational intervention incorporating key MI elements. CG115 is alcohol-specific, not a blanket all-substances endorsement.

    Scope: People who misuse alcohol, at initial assessment

    Source checked

  • Enhancing motivation for change in substance use disorder treatment (TIP 35)

    SAMHSA · Updated 2019; PEP19-02-01-003 · Professional reference · Executive summary; Chapter 3

    Discussed in the source

    TIP35 gives clinical implementation guidance for motivational interviewing. Label it as a SAMHSA treatment manual, not a graded CPG recommendation.

    Scope: Substance-use-disorder treatment

    Source checked

  • Clinical Practice Guideline for the Management of Substance Use Disorders

    VA/DoD · August 2021; version 5.0 · Clinical guideline · Appendix C, section F, p.117; recommendations 15 and 23

    Discussed in the source

    The guideline distinguishes MI from MET, which adds systematic assessment and personalized feedback. Its named MET recommendations should not be read as separate recommendations for every use of MI.

    Scope: MI principles within structured motivational enhancement therapy for substance-use disorders.

    Source checked

  • Clinical Practice Guideline for Tobacco Use Treatment

    VA/DoD · January 2026; version 3.0 · Clinical guideline · Recommendation 1; pp.35, 39–40; Appendix I, p.129

    Recommendation for the stated population

    VA/DoD weakly recommends MI to increase treatment engagement. This recommendation concerns entering treatment, rather than the abstinence effect of MI used alone.

    Scope: Adults who use tobacco or nicotine; engagement in cessation treatment.

    Source checked

  • Mental Health Gap Action Programme (mhGAP) guideline for mental, neurological and substance use disorders

    World Health Organization · Third edition, 20 November 2023 · Clinical guideline · DRU3 justification and remarks, p. 70 (PDF p. 102)

    Discussed in the source

    WHO discusses motivational interviewing findings, but the recommendation names CBT and contingency management. Inclusion in the review is not a separate recommendation for MI.

    Scope: Adults with cocaine or stimulant dependence.

    Source checked

  • Mental Health Gap Action Programme (mhGAP) guideline for mental, neurological and substance use disorders

    World Health Organization · Third edition, 20 November 2023 · Clinical guideline · ALC2, pp. 13–14 (PDF pp. 45–46)

    Discussed in the source

    Motivational interviewing is discussed within the reviewed psychosocial interventions. WHO conditionally recommends structured psychosocial treatment as a group, with low-certainty evidence, while noting uncertainty about individual therapy types versus usual care.

    Scope: Adults with alcohol dependence.

    Source checked

Family Systems

Multisystemic Therapy

Scott Henggeler · 1998

Guidelines and official sources (1)

1 professional reference check

Read the recommendation and its scope. A source may discuss an approach without recommending it.

  • Screening and treatment of substance use disorders among adolescents

    SAMHSA · 2021 advisory; PEP20-06-04-008 · Professional reference · Treatment table, page 7

    Discussed in the source

    SAMHSA describes MST in a treatment advisory; this is not a generic all-childhood-disorders CPG grade.

    Scope: Adolescents with severe SUD and delinquent or violent behaviour

    Source checked

Cognitive-Behavioral

Seeking Safety

Lisa Najavits · 2002

Guidelines and official sources (2)

2 clinical guideline checks

Read the recommendation and its scope. A source may discuss an approach without recommending it.

  • Clinical Practice Guideline for the Treatment of Posttraumatic Stress Disorder in Adults

    American Psychological Association · Approved February 2025; 2025 update · Clinical guideline · PTSD and substance-use disorder, printed p.15 (PDF p.19): usual-care comparison

    Discussed in the source

    APA reports no difference in effect on PTSD symptoms or substance use and makes no recommendation for or against these comparisons.

    Scope: Adults with PTSD and co-occurring SUD; Seeking Safety, with or without usual care, compared with usual SUD care.

    Source checked

  • Clinical Practice Guideline for the Treatment of Posttraumatic Stress Disorder in Adults

    American Psychological Association · Approved February 2025; 2025 update · Clinical guideline · PTSD and substance-use disorder, printed p.15 (PDF p.19): active comparisons

    Insufficient evidence for or against

    APA finds insufficient evidence to prefer either side of these active-treatment comparisons.

    Scope: Adults with PTSD and co-occurring SUD; Seeking Safety compared with COPE or Creating Change in the reviewed care arrangements.

    Source checked

Postmodern

Solution-Focused Brief Therapy

de Shazer / Insoo Kim Berg · 1985

Guidelines and official sources (1)

1 professional reference check

Read the recommendation and its scope. A source may discuss an approach without recommending it.

  • TIP 39: Substance Use Disorder Treatment and Family Therapy, Chapter 3

    SAMHSA · 2020 update · Professional reference · Chapter 3: Solution-Focused Brief Therapy

    Discussed in the source

    SAMHSA TIP 39 discusses solution-focused brief therapy and supporting research. This is a treatment-improvement reference rather than an unspecified registry endorsement.

    Scope: Families affected by substance-use problems.

    Source checked

Family Systems

Strategic Family Therapy

Jay Haley / Cloe Madanes · 1973

Guidelines and official sources (1)

1 clinical guideline check

Read the recommendation and its scope. A source may discuss an approach without recommending it.

  • Alcohol-use disorders: diagnosis, assessment and management (CG115)

    NICE · 2011 · Clinical guideline · Recommendations 1.3.7.8 and 1.3.7.11

    Discussed in the source

    NICE names Brief Strategic Family Therapy within multicomponent care. This supports the specific BSFT intervention and population, not all forms of Strategic Family Therapy.

    Scope: BSFT for ages 10–17 with alcohol misuse and significant comorbidity or limited support.

    Source checked

Assessment not yet completed (13)

No completed assessment or source check for this topic is recorded yet.

Psychedelic

EMBARK

Brennan / Belser · 2022

Somatic

Neurofeedback

Joe Kamiya / Barry Sterman / Joel Lubar · 1968

Additional Source References (5)

These source checks also address this topic. They are listed separately from the catalogue associations above. Read each source’s scope and direction; a mention may concern a related intervention or a neutral recommendation.

Cognitive-Behavioral

Behavioral Activation

Guidelines and official sources (1)

1 clinical guideline check

Read the recommendation and its scope. A source may discuss an approach without recommending it.

  • Clinical Practice Guideline for Tobacco Use Treatment

    VA/DoD · January 2026; version 3.0 · Clinical guideline · Recommendation 15; pp.36, 53–54

    Insufficient evidence for or against

    VA/DoD reviews behavioral activation and finds insufficient evidence to prefer another counseling approach over standard CBT. This finding is specific to comparative tobacco-cessation treatment.

    Scope: Behavioral activation adapted for tobacco cessation, compared with standard CBT.

    Source checked

Integrative

Clinical Hypnotherapy

Guidelines and official sources (1)

1 clinical guideline check

Read the recommendation and its scope. A source may discuss an approach without recommending it.

  • Clinical Practice Guideline for Tobacco Use Treatment

    VA/DoD · January 2026; version 3.0 · Clinical guideline · Recommendation 28; pp.38, 70–72

    Recommendation against the stated use

    VA/DoD weakly recommends against hypnotherapy as standalone cessation treatment. The recommendation does not address every adjunctive use of hypnosis or its use for other conditions.

    Scope: Hypnotherapy used alone to achieve abstinence from tobacco or nicotine.

    Source checked

Cognitive-Behavioral

Mindfulness-Based Cognitive Therapy

Guidelines and official sources (1)

1 clinical guideline check

Read the recommendation and its scope. A source may discuss an approach without recommending it.

  • Clinical Practice Guideline for Tobacco Use Treatment

    VA/DoD · January 2026; version 3.0 · Clinical guideline · Recommendation 28; Table 4, p.38; discussion pp.70–72

    Discussed in the source

    VA/DoD weakly recommends against standalone mindfulness for this cessation goal. This is category-level guidance; MBCT is not separately graded, and the statement does not address adjunctive use or other conditions.

    Scope: Mindfulness used as a standalone treatment for abstinence from tobacco or nicotine.

    Source checked

Integrative

Mindfulness-Based Stress Reduction

Guidelines and official sources (1)

1 clinical guideline check

Read the recommendation and its scope. A source may discuss an approach without recommending it.

  • Clinical Practice Guideline for Tobacco Use Treatment

    VA/DoD · January 2026; version 3.0 · Clinical guideline · Recommendation 28; Table 4, p.38; discussion pp.70–72

    Discussed in the source

    VA/DoD weakly recommends against standalone mindfulness for this cessation goal. This is category-level guidance; MBSR is not separately graded, and the statement does not address adjunctive use or other conditions.

    Scope: Mindfulness used as a standalone treatment for abstinence from tobacco or nicotine.

    Source checked

Cognitive-Behavioral

Prolonged Exposure Therapy

Guidelines and official sources (1)

1 clinical guideline check

Read the recommendation and its scope. A source may discuss an approach without recommending it.

  • Clinical Practice Guideline for the Treatment of Posttraumatic Stress Disorder in Adults

    American Psychological Association · Approved February 2025; 2025 update · Clinical guideline · PTSD and substance-use disorder, printed p.15 (PDF p.19)

    Recommendation for the stated population

    APA strongly recommends this combination; the table includes PE plus usual care and the COPE protocol.

    Scope: Adults with PTSD and co-occurring SUD; PE-based treatment plus usual SUD care versus usual SUD care alone.

    Source checked


Cases Featuring Associated Approaches

These teaching cases share approach links with this topic. They may illustrate a different presenting concern.


Reading This Page

Why are these approaches listed with Substance Use & Addictions?

The catalogue associates 29 approaches and 0 frameworks with this topic. These links support learning and comparison; association alone is not a treatment recommendation or evidence of effectiveness.

How should I read the evidence assessments?

Assessments are specific to the population and scope stated on each card. They include a rationale, source links, and a review date. An overall review of an approach does not automatically apply to this condition, and a randomized-study label does not by itself mean that a study found benefit.

What does "Assessment not yet completed" mean?

A condition-specific assessment has not been recorded. Approaches with checked sources appear in a separate assessment-pending group; a checked source can support, oppose, or discuss an intervention without recommending it. Neither pending group means that no research exists or that the approach is ineffective. Frameworks are shown separately.


Sources and Review Scope

Source links and dates on assessment cards apply to the stated population and rationale. The clinical overview and prevalence text above are separate authored content; an approach's evidence label does not verify those statements. Recorded narrative notes and citations remain available on individual modality pages, with their review status identified. The bibliography provides further reading.